Detalhe da pesquisa
1.
High prevalence of heteroresistance in Staphylococcus aureus is caused by a multitude of mutations in core genes.
PLoS Biol
; 22(1): e3002457, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38175839
2.
Theoretical considerations and empirical predictions of the pharmaco- and population dynamics of heteroresistance.
Proc Natl Acad Sci U S A
; 121(16): e2318600121, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38588431
3.
Suppression of the E. coli rnpA49 conditionally lethal phenotype by different compensatory mutations.
RNA
; 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38688559
4.
Low levels of tetracyclines select for a mutation that prevents the evolution of high-level resistance to tigecycline.
PLoS Biol
; 20(9): e3001808, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36170241
5.
Pervasive Selection for Clinically Relevant Resistance and Media Adaptive Mutations at Very Low Antibiotic Concentrations.
Mol Biol Evol
; 40(1)2023 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36627817
6.
A novel type of colistin resistance genes selected from random sequence space.
PLoS Genet
; 17(1): e1009227, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33411736
7.
Molecular mechanisms of collateral sensitivity to the antibiotic nitrofurantoin.
PLoS Biol
; 18(1): e3000612, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31986134
8.
CombiANT: Antibiotic interaction testing made easy.
PLoS Biol
; 18(9): e3000856, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32941420
9.
Dynamics of Extensive Drug Resistance Evolution of Mycobacterium tuberculosis in a Single Patient During 9 Years of Disease and Treatment.
J Infect Dis
; 225(6): 1011-1020, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33045067
10.
Prevalence of colistin heteroresistance in carbapenem-resistant Pseudomonas aeruginosa and association with clinical outcomes in patients: an observational study.
J Antimicrob Chemother
; 77(3): 793-798, 2022 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34918135
11.
Evolutionary Trajectories to Antibiotic Resistance.
Annu Rev Microbiol
; 71: 579-596, 2017 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28697667
12.
Evolution of a New Function by Fusion between Phage DNA and a Bacterial Gene.
Mol Biol Evol
; 37(5): 1329-1341, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31977019
13.
Selection of Resistant Bacteria in Mallards Exposed to Subinhibitory Concentrations of Ciprofloxacin in Their Water Environment.
Antimicrob Agents Chemother
; 65(3)2021 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33318021
14.
Evolutionary consequences of drug resistance: shared principles across diverse targets and organisms.
Nat Rev Genet
; 16(8): 459-71, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26149714
15.
Cellular hysteresis as a principle to maximize the efficacy of antibiotic therapy.
Proc Natl Acad Sci U S A
; 115(39): 9767-9772, 2018 09 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30209218
16.
Mutations that increase expression of the EmrAB-TolC efflux pump confer increased resistance to nitroxoline in Escherichia coli.
J Antimicrob Chemother
; 75(2): 300-308, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31633764
17.
Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging.
Proc Natl Acad Sci U S A
; 114(34): 9170-9175, 2017 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28790187
18.
Structural and functional innovations in the real-time evolution of new (ßα)8 barrel enzymes.
Proc Natl Acad Sci U S A
; 114(18): 4727-4732, 2017 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28416687
19.
Experimental Determination and Prediction of the Fitness Effects of Random Point Mutations in the Biosynthetic Enzyme HisA.
Mol Biol Evol
; 35(3): 704-718, 2018 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29294020
20.
Upregulation of PBP1B and LpoB in cysB Mutants Confers Mecillinam (Amdinocillin) Resistance in Escherichia coli.
Antimicrob Agents Chemother
; 63(10)2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31332059